Tuesday, December 27, 2005

What Happened To The Donations To The RRF?

The RRF has divested itself of all available funds by making a further contribution of $4265.32 towards the approved research grant that was announced on October 12.

Monday, December 19, 2005

In the news: Rosacea Research Foundation

The following appeared on the Rosacea Research Foundation web site:

The RRF is no longer accepting donations and is winding down with the aim of filing our disolution papers by December 31.

It's sad to think that a foundation that started with such promise and high expectations has disolved in such a short time.

Friday, December 16, 2005

CollaGenex To Purchase SansRosa

Skin treatment maker CollaGenex Pharmaceuticals Inc. said Thursday that it agreed to acquire SansRosa Pharmaceutical Development Inc., which holds patent applications for methods of treatment of redness associated with rosacea and other skin disorders, for up to about $6.75 million.
An initial payment of $750,000 will give CollaGenex 51 percent of the Philadelphia startup.
Shareholders could get up to an additional $4 million to $6 million if all milestones are met and a patented product is developed and approved for sale, Collagenex said.

Tuesday, December 13, 2005

Perioral Dermatitis May Be Confused With Rosacea

Perioral (around the mouth) dermatitis is a skin rash of small red bumps that may itch and burn. It may also involve the chin and facial lines around the nose. It may look like acne with its pustules, but it’s not.
There are a number of theories as to why perioral dermatitis occurs. One is that it is a form of rosacea. Hormonal fluctuations, sunlight, stress, makeup, heavy facial creams, fluoridated toothpaste, steroid nasal sprays/inhalers, and overuse of steroid creams are known to aggravate perioral dermatitis. Foods or pills like Synthroid are not believed to cause or worsen perioral dermatitis.
Steroid creams are a surprising cause of worsening perioral dermatitis. While steroid creams can help with an acute flare, the rash returns with a vengeance once the steroid cream is stopped. This is a difficult “addiction” because stopping cold turkey results in weeks of a worsened rash. Nonetheless, topical antibacterial creams and lotions are better in the long run.
For stubborn cases, oral antibiotics like Doxycycline or Flagyl are your best bet. Steroid creams (those that are non-fluorinated) and immune-suppressing creams like Elidel or Protopic are best used for short periods until the topical/oral antibiotics have kicked in. One more suggestion is to use a mild skin cleanser like Dove or Cetaphil and avoid scrubbing.

Thursday, December 08, 2005

Avoiding Rosacea Triggers

What do Bill Clinton, Renee Zellweger and William Shatner all have in common? They each have rosacea, a skin disease which causes reddening on the face, according to a rosacea Web site.
One famous individual, W.C. Fields, is the poster person for one of the more severe forms of rosacea known as rhinophyma. Estimates are that 14 million of us experience rosacea in the U.S. each year. The majority don't recognize it as a treatable condition.
As with many diseases, rosacea has a spectrum of severity. The mildest cases are manifested by blushing and redness of the face triggered by sun, stress, alcohol and other influences.
In those with rosacea, this may progress to more permanent red markings, either acne-like spots on the face and nose, or prominent blood vessels (spider veins). In some cases, this leads to thickening of the skin, forming a prominent bulbous nose like actors W.C. Fields and Karl Malden.
Rosacea may also be present with symptoms related to the eyelids or the eyes themselves. Redness, irritation and symptoms like conjunctivitis may herald the onset of rosacea. Of course, this usually is persistent or recurrent, in contrast with a single episode of viral conjunctivitis.
Fortunately there is treatment available for this disease. The foundation of treatment is identification and avoidance of triggers. Avoiding excessive sun, spicy food and or hot environments may reduce symptoms and slow progression of the disease. Often skin products that are harsh or drying can trigger symptoms, so avoid alcohol-based or abrasive products.
Medical treatment usually includes oral or topical antibiotics. While oral treatment is generally more effective, side effects such as yeast infections or GI upset may limit its usefulness. As soon as rosacea is under control, it is important to taper to the lowest effective dose or switch to a topical antibiotic. This serves to minimize the risk of side effects.
In severe cases of rosacea or rhinophyma, surgery or laser therapy may be performed to reduce evidence of the disease. Cosmetics that mask the redness often provide adequate coverage.
It's important to note that rosacea is not caused by a hygiene issue or alcohol abuse. Indeed, overzealous washing of the skin may actually trigger the rosacea flare. And while drinking alcohol may cause a flare of rosacea, the vast majority of people with visible rosacea do not have an alcohol problem.
Potential triggers fall into several general categories: heat and cold, foods and alcohol, and things that stress the skin directly. Examples of the latter category include sun exposure, skin products, scrubbing the skin and life stress.
Foods and alcohol include different items for different people. For some, it's spicy foods, yet for others certain fruits or vegetables may trigger the redness. Avoiding heat and cold stress is harder than you may think - even hot beverages, hot weather, a hot shower or heat from exercise may trigger a reaction. Cold weather and wind can cause it as well.
Because there is such variability in what triggers the symptoms in any individual, it is wise to record a "rosacea diary," available from the National Rosacea Society. This helpful tool lists the most common triggers and allows you to evaluate your symptoms after exposure to a trigger.
If you find your rosacea is improving the more you avoid an item or activity, it's a safe bet that it is a trigger for you.
Bottom line with rosacea is that it is important to recognize the disease early. Avoidance of triggers and early medical treatment can reduce the impact of symptoms in the future.

Thursday, December 01, 2005

The Red Nose Syndrome

Winter can certainly wreak havoc on your skin, with colder temperatures and lower levels of humidity leading to drier air and drier skin, not to mention frequent colds and nose-blowing. There are times, however, when it is hard to discern the difference between a winter nuisance and an ongoing skin condition. For instance, what you perceive to be redness from harsh winds or chapped skin due to the common cold could actually be a persistent redness that is a sign of a skin disease called rosacea. Since cold weather and strong winds are triggers that can aggravate rosacea, there is a possibility that the redness may not be what you think.
According to the experts at Galderma, persistent redness across the cheeks, nose, forehead and chin can be an early warning sign of rosacea, and at this stage, it is usually easier to arrest its progress. The key is to detect the persistent redness and act on it. By recognizing the problem and seeing a dermatologist, you can begin treatment. The key is to give a dermatologist a call once the redness persists to the point that it has become a personal concern. A dermatologist can accurately assess the problem.